抗精神失常药物致肥胖和糖尿病的风险

郝杰a,柳洁b

中国药学杂志 ›› 2013, Vol. 48 ›› Issue (11) : 934-936.

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中国药学杂志 ›› 2013, Vol. 48 ›› Issue (11) : 934-936. DOI: 10.11669/cpj.2013.11.022
药物与临床

抗精神失常药物致肥胖和糖尿病的风险

  • 郝杰a,柳洁b
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摘要

目的 阐述第二代抗精神病药对患者体重、血糖、血脂等的影响。方法 通过整理国内外相关文献,对近年来第二代抗精神病药促使患者体重增加、糖尿病及高甘油三酯血症等的发生,并可导致心血管疾病、脑血管疾病,继而影响抗精神病治疗的依从性以及精神疾病患者的转归进行回顾、总结。结果与结论 第二代抗精神病药可以极大提高精神病治疗的有效性和患者的耐受性,但其可能增加肥胖及糖尿病发生风险,应对使用第二代抗精神病药的患者开展糖尿病、心血管疾病风险的基础筛查工作,同时配合饮食、锻炼及药物治疗,共同提高严重精神疾病患者的生活质量。

关键词

第二代抗精神疾病药物 / 糖尿病 / 肥胖 / 高甘油三酯血症

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郝杰a,柳洁b. 抗精神失常药物致肥胖和糖尿病的风险[J]. 中国药学杂志, 2013, 48(11): 934-936 https://doi.org/10.11669/cpj.2013.11.022
中图分类号: R969.3   

参考文献

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